Study of Rubella Immunity. Response to Vaccination of Subjects With Very Low, Equivocal or Undetectable Titers of Rubella Virus Antibodies
This trial is active, not recruiting.
|Treatment||determination of anti-rubella antibody, e1|
|Start date||February 2012|
|End date||May 2014|
|Trial size||192 participants|
|Trial identifier||NCT02934295, 2011-A01445-36, 2011/61|
The aim of the research is to study humoral and cellular immunity in pregnant women for who the level of rubella virus antibodies is weakly positive, equivocal or negative with the usual laboratory technique.
|Intervention model||single group assignment|
Level of Anti-Rubella Antibody, E1
time frame: 8 months
Female participants at least 18 years old.
Inclusion Criteria: - Women over 18 - Rubella serology negative, ambiguous or weakly positive during a first prenatal consultation and for which the second determination of the immunity anti rubella is necessary after 18 weeks of pregnancy - Accepting the rubella vaccination after the childbirth; - Accepting a blood test, during a postnatal consultation, 6 in 8 weeks after vaccination, to verify their immunity towards the virus of the rubella. - Affiliated to a social security scheme - Having given a written consent Exclusion Criteria: - Rubella contracted since the first serology realized during the first prenatal consultation - Autoimmune pathologies - Intolerance / allergy known about a previous vaccination whatever it is - Immunosuppression (HIV, transplants) - Injection of multivalent immunoglobulins (except anti-D)
|Official title||Study of Rubella Immunity. Response to Vaccination of Subjects With Very Low, Equivocal or Undetectable Titers of Rubella Virus Antibodies|
|Principal investigator||Olivier Picone|
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