Study of Anesthesia Costs and Recovery Profiles
This trial is active, not recruiting.
|Sponsor||University of Pecs|
|Start date||September 2014|
|End date||October 2016|
|Trial size||120 participants|
|Trial identifier||NCT02920749, 316-2336/KK15|
The purpose of this study is to compare the perioperative hemodynamic parameters, recovery profiles and cost containment of sevoflurane and propofol based general anesthesia for otorhinolaryngeal surgery.
|Endpoint classification||safety/efficacy study|
|Intervention model||parallel assignment|
|Masking||single blind (subject)|
drug consumption of anesthesia
time frame: two years
costs of anesthesia
time frame: two years
Male or female participants from 18 years up to 65 years old.
Inclusion Criteria: - ASA physical status grade I or II who were scheduled for elective otorhinolaryngological surgery. Exclusion Criteria: - Individuals with a history of bronchial asthma, chronic obstructive pulmonary disease, epilepsy, psychiatric illness, cerebrovascular or congenital neuromuscular disease.
|Official title||Recovery Profiles and Costs in Sevoflurane and Propofol Based Anesthesia|
|Description||Sevoflurane and propofol are two basic drugs in the maintenance of anesthesia. In this study we compared the perioperative hemodynamic parameters, recovery profiles and cost containment of sevoflurane and propofol based general anaesthesia for otorhinolaryngeal surgery. Patients were equally divided into four anaesthetic subgroups. In groups A and C anaesthesia was based on sevoflurane or propofol, respectively, without bispectral index (BIS) and train-of-for monitor (TOF) monitoring. In groups B and D anaesthesia was based on sevoflurane or propofol, respectively, with BIS and TOF monitoring. Drug consumption, recovery profiles and anaesthesia costs were analysed. ECG, main arterial pressure (MAP), heart rate, oxygen saturation of peripheral haemoglobin (SpO2), pressure of end-tidal carbon dioxide was monitored continuously and registered at 5 min intervals during anaesthesia. Each group received propofol for anaesthesia induction. In group A and B anaesthesia was maintained with sevoflurane, in groups C and D with propofol. . In groups B and D the depth of anaesthesia (BIS® Quatro Brain Monitoring Sensor, Covidien) and the neuromuscular blocking status (Infinity®, Trident® NMT SmartPod®, Dräger Medical) were monitored too. BIS and TOF values were recorded at 5 min intervals.|
Call for more information