Side of Embryo Biopsy Interfering Implantation Potential
This trial is active, not recruiting.
|Treatments||vegetal pole blastomer embryo, animal pole blastomer embryo|
|Sponsor||Ahmad Mustafa Mohamed Metwalley|
|Collaborator||Ibn Sina Hospital|
|Start date||January 2015|
|End date||August 2016|
|Trial size||100 participants|
|Trial identifier||NCT02902614, Embryo Biopsy|
Selection of side of embryo biopsy that will not interfering with implantation power of developed blastocyst embryo during biopsy procedure arranged for PGT.
|United States||No locations recruiting|
|Other Countries||No locations recruiting|
|Endpoint classification||safety/efficacy study|
|Intervention model||crossover assignment|
|Primary purpose||supportive care|
blastocyst location of ICM at day 5
time frame: 2 months
time frame: 2 months
Male or female participants of any age.
Inclusion Criteria: - grade 1 or 2 embryos at eight cell stage or 8-1/ 8-2 embryo quality. Exclusion Criteria: - grade 3 embryo at day 3, or 8-3 embryos.
|Official title||Effect of Embryo Biopsy Side on Post Biopsy Blastocyst Structurs and Implantation|
|Principal investigator||Ahmad M Metwalley|
|Description||During process of embryo biopsy, it was indicated to avoid contacting cells closer to inner cell mass as it can decrease the quality of embryo and its structural composition. However, recommendation for collection from the trophectoderm (TE) side is indicated. Absence of differentiation during cleavage-stage or morula stage at day 3 and day 4 respectively, will present the needful to focus a specific location for embryo biopsy during pre-blastocyst stages for embryo going to do genetic testing before implantation or embryo transfer. In articulation around the second polar body or the animal pole of embryo, collection of the cell from the vegetal pole in crospondence to avoide collection form the animal pole is to be compare the results of implantation for biopsy done using the animal pole side or the random non organized biosy procedure.|
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