This trial is active, not recruiting.

Conditions bronchiolitis obliterans, bone marrow transplantation
Treatment forced oscillations measure
Sponsor Hopital Foch
Start date June 2011
End date September 2015
Trial size 110 participants
Trial identifier NCT02902471, 2010-A01229-30, 2010/48


A study to evaluate the role of forced oscillations in diagnosis of bronchiolitis obliterans syndrome in patients after bone marrow transplantation. The force oscillations technique will be compared with classical spirometry.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Intervention model single group assignment
Masking open label
Primary purpose diagnostic
Patients with bronchiolitis obliterans syndrome after bone marrow transplantation
forced oscillations measure

Primary Outcomes

Number of days
time frame: 2 years

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Patients over 18 years - Bone marrow or hematopoietic stem cells transplantation for more than 100 days - Clinical stability - Patients affiliated to a social security system - Patients having given his (her) written consent. Exclusion Criteria: - Bronchiolitis Obliterans already diagnosed - Unresolved Respiratory infection - Unresolved mechanical complication (pneumothorax, effusions) - Medicinal pneumopathy - Inability to perform pulmonary function tests

Additional Information

Official title Functional Evaluation of Distal Airways by Forced Oscillations: Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation
Principal investigator Jean-Louis Couderc, MD, PhD
Trial information was received from ClinicalTrials.gov and was last updated in September 2016.
Information provided to ClinicalTrials.gov by Hopital Foch.