Continuous Versus Intermittent Oxytocin for Induction of Labor: A Randomized Study
This trial is active, not recruiting.
|Condition||intemittant, continue, oxytocin|
|Sponsor||Zeynep Kamil Maternity and Pediatric Research and Training Hospital|
|Start date||August 2016|
|End date||October 2016|
|Trial size||200 participants|
|Trial identifier||NCT02859571, 152|
This study evaluates continuous oxytocin versus intermittent oxytocin for induction of labor at term. Half of participants will be taken continuous oxytocin, while the other half will be taken intermittent oxytocin.
|Endpoint classification||safety/efficacy study|
|Intervention model||parallel assignment|
time frame: intraoperative
Female participants from 18 years up to 40 years old.
Inclusion Criteria: - singleton pregnancy, - 37≤ weeks of gestational age , - vertex presentation, - women with cervical dilation 3 cm - no contraindication to vaginal delivery. Exclusion Criteria: - fetal malpresentation, - multifetal pregnancy, - more than three contractions in 10 minutes, - contraindications to oxytocin, - a category II or III fetal heart rate pattern, - fetal anomaly, - fetal demise - women with immediate delivery indications
|Description||In the continuous oxytocin group, traditional treatment of oxytocin used at a starting dose of 1-2 mIU/min and the dose was increased by 2 mIU/min at every 15 minutes until regular contractions obtained at a rate of 3-5 contractions in a 10-minute period. The maximum dose of oxytocin was 40 mIU/min and oxytocin was administered until delivery. In the intermittent group, oxytocin was discontinued when cervical dilation was 5 cm and 2 hours after discontinuation oxytocin was reused at a starting dose of 1-2 mIU/min and was increased as the same protocol used for continuation oxytocin group.|
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