Effects of Dexmedetomidine on Oxygenation and Lung Mechanics in Morbidly Obese Patients Undergoing Bariatric Operations
This trial is active, not recruiting.
|Condition||restrictive lung disease|
|Treatments||dexmedetomidine, normal saline|
|Start date||September 2016|
|End date||July 2017|
|Trial size||50 participants|
|Trial identifier||NCT02843698, N-12-2016|
The study aims to investigate the effect of dexmedetomidine on oxygenation and lung mechanics in morbidly obese patients
|Endpoint classification||pharmacodynamics study|
|Intervention model||parallel assignment|
|Masking||double blind (subject, caregiver, investigator, outcomes assessor)|
time frame: after induction of anesthesia and every 30 minutes till the end of the operation
time frame: after induction of anesthesia and then every 30 minutes till the end of the operation
Male or female participants from 18 years up to 65 years old.
Inclusion Criteria: - Morbid obese (body mass index > 40) with documented restrictive lung disease scheduled to bariatric operation. Exclusion Criteria: - Heart failure - ِِِِArrhythmia - Heart block - Severe liver or kidney impairment.
|Official title||Effects of Dexmedetomidine on Oxygenation and Lung Mechanics in Morbidly Obese Patients Undergoing Bariatric Operations: A Randomized Controlled Trial|
|Description||The patients of interest are morbid obese patients scheduled for bariatric surgery. Dexmeditomidine will be infused intraoperatively after induction of anesthesia. lung mechanics (dead space and compliance) as well as oxygenation (PF ratio) will be monitored intraoperatively and postoperatively|
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