Study of A Special Vessel Subtype in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture
This trial is active, not recruiting.
|Condition||femoral neck fractures|
|Treatment||total hip arthroplasty or proximal femoral nails|
|Sponsor||Second Affiliated Hospital of Soochow University|
|Start date||March 2016|
|End date||February 2018|
|Trial size||30 participants|
|Trial identifier||NCT02750046, SencondSoochowU|
RATIONALE: Collecting and storing bone samples from patients with osteoporotic and nonosteoporotic fracture to study a special vessel subtype in the laboratory may help surgeon learn more about the relationship between bone mineral density (BMD) and a special vessel subtype (type H vessel).
PURPOSE: This research study is looking at changes of a special vessel subtype in bone samples from patients with osteoporotic and nonosteoporotic fracture.
|Intervention model||parallel assignment|
|Masking||single blind (subject)|
The area of a special vessel subtype in human bone samples
time frame: 3 months
The value of bone mineral density
time frame: 1 week
Correlation of of bone mineral density and area of a special vessel subtype in human bone
time frame: 2 months
Female participants from 60 years up to 75 years old.
Inclusion Criteria: 1. Ages Eligible for Study: 65-75 Years 2. Genders Eligible for Study: Woman 3. Accepts Healthy Volunteers: NO 4. Study Population: Female patients with hip fracture. - Exclusion Criteria: 1. Malignancy or benign ovarian cysts 2. Known chronic or systemic diseases 3. Hormone therapy in the previous 3 months 4. Bone metabolism and drug therapy
|Official title||Collection of Bone Specimens for Testing of A Special Vessel Subtype|
|Description||OBJECTIVES: 1. Establish type H vessel in bone specimen in patients with hip fracture. 2. Explore the correlation of BMD and type H vessel. OUTLINE: 1. Collect human bone specimens from patients with Osteoporotic and Nonosteoporotic Fracture. 2. Provide a repository for storage of tissue and make these specimens available for approved projects by laboratory-based investigators. 3. Observe the type H vessel in bone slice by immunofluorescence staining. 4. Collect clinical data on these patients including bone mineral density. 5. Investigate the relationship between BMD and type H vessel.|
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