Social and Emotional Brain Function in Cannabis Users
This trial has been completed.
|Sponsor||University of Electronic Science and Technology of China|
|Collaborator||German Research Foundation|
|Start date||July 2015|
|End date||December 2016|
|Trial size||43 participants|
|Trial identifier||NCT02711371, ART_Can_01|
The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a 28 supervised abstinence period. Previous research in cannabis users has predominantly focused on cognitive functions. Moreover, studies have implicated that observed deficits in cannabis users may regenerate after a prolonged abstinence period. Findings might provide important information with respect to relapse vulnerability.
Cannabis dependent individuals according to DSM 4 criteria, aged 18-40 years
Healthy controls, socio-demographically matched
fMRI neural activation patterns of social-emotional brain processes after 28 day abstinence
time frame: one timepoint = fMRI assessment after 28 day abstinence period
Ratings of subjective experience (pleasantness, rewarding value) will be assessed after 28 days of abstinence
time frame: one timepoint = during fMRI assessment after 28 day abstinence period
Relapse interview assessed with Timeline-Followback Method
time frame: one timepoint = 24 months post-fMRI-session
All participants from 18 years up to 40 years old.
Inclusion Criteria: - Cannabis dependence according to DSM 4 criteria - 28 days of supervised abstinence Exclusion Criteria: - other DSM 4 diagnosis - neurological disorders
|Official title||Long-term Effects of Cannabis Use on Social and Emotional Brain Processes in Dependent Cannabis Users After a 28 Day Abstinence Period|
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