Overview

This trial is active, not recruiting.

Condition energy expenditure during ramadan fasting
Sponsor Imperial College London Diabetes Centre
Start date June 2015
End date June 2016
Trial size 45 participants
Trial identifier NCT02696421, IREC 022

Summary

Ramadan fasting entails abstinence from eating and drinking between dawn and sunset. During this month major changes in meal times and patterns, sleeping times and activity occur. Starvation is known to lead to a compensatory reduction in energy expenditure. However, the Ramadan fast is not synonymous with starvation as it involves intermittent periods of fasting followed by gorging. People who fast during Ramadan feel less energetic. However, little is known about the effects of this religious practice on energy metabolism. .

The aim of this study is to assess energy dynamics before and/or after and during Ramadan fasting in non-obese participants. Resting metabolic rate (RMR), thermic effect of food (TEF), active energy expenditure (AEE) and total energy expenditure (TEE) in free-living conditions will be measured . Indirect calorimetry will be used to assess RMR and TEF, doubly labeled water will be used to measure TEE and activity monitors will measure physical activity. In addition, body composition analysis will be performed by bio-electrical impedance. Blood sample will be taken to exclude medical factors affecting energy metabolism.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model case-only
Time perspective prospective
Arm

Primary Outcomes

Measure
Resting metabolic rate
time frame: 3 months
24 hour energy expenditure
time frame: 3 months

Eligibility Criteria

Male or female participants from 18 years up to 70 years old.

Inclusion Criteria: - Willing to participate. - Age (18-70) years. - BMI (20-30 kg/m2). - Physically and mentally healthy. - Consent form signed. Exclusion Criteria: - Any patients with significant health problem. - Pregnant and lactating females. - Smokers. - Consumption of caffeine before tests. - Patients who have had vigorous exercise for the last 12 hours before visit. - Patients with diabetes treated with drugs known to alter the metabolic rate. - Patients who had bariatric surgery. - Patients with eating disorders. - Patients with conditions known to affect energy expenditure - Patients on medication know to alter EE (Thyroxine, anti-thyroid drugs, certain cold remedies)

Additional Information

Official title Ramadan and Energy (RAMEE) Study
Trial information was received from ClinicalTrials.gov and was last updated in February 2016.
Information provided to ClinicalTrials.gov by Imperial College London Diabetes Centre.