This trial is active, not recruiting.

Condition blood pressure
Treatment soluble fibre
Sponsor St. Michael's Hospital, Toronto
Start date September 2014
End date September 2015
Trial size 500 participants
Trial identifier NCT02670967, FIberBPMeta


The present study conducted a meta-analysis of 22 randomly controlled trials to assess the effects of soluble fiber intake on blood pressure in human subjects.

Using the Cochrane Handbook for Systematic Reviews of Intervention, a systematic review and meta-analysis was conducted. Information regarding study methods, characteristics, mean BP and standard deviations were extracted The data from each study were pooled using a random effects model to estimate the effects of soluble fiber consumption on blood pressure.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Time perspective retrospective

Primary Outcomes

Systolic Blood Pressure
time frame: 4 weeks
Diastolic Blood Pressure
time frame: 4 weeks

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - Randomized Controlled Trials - Parallel or Crossover Design - Duration: >3 weeks - Human trials - Viscous (soluble) fiber - Viable endpoint data - Articles published in English Exclusion Criteria: - Non-human - Non-randomized - Lack of control - Less than 4 weeks in duration - No viable endpoint data

Additional Information

Official title Effects of Soluble Fiber on Blood Pressure: A Meta-analysis of Randomly-controlled Trials
Principal investigator Vladimir Vuksan, PhD
Trial information was received from ClinicalTrials.gov and was last updated in February 2016.
Information provided to ClinicalTrials.gov by St. Michael's Hospital, Toronto.