This trial is active, not recruiting.

Conditions type 2 diabetes, obesity
Treatments short biliarypancreatic limb, long biliarypancreatic limb
Sponsor Weidong Tong
Start date January 2016
End date January 2016
Trial size 50 participants
Trial identifier NCT02667652, 776117


The purpose of this study is to investigate the curative effect of the length of the jejunum exclusion in gastric surgry for T2DM and metabolic syndrome,and to draft Scientific and reasonable operation parameters.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification safety/efficacy study
Intervention model parallel assignment
Masking single blind (investigator)
Primary purpose treatment
(Active Comparator)
short biliarypancreatic limb
short biliarypancreatic limb
biliarypancreatic limb:50cm;roux limb:150cm.
(Active Comparator)
long biliarypancreatic limb
long biliarypancreatic limb
biliarypancreatic limb:100cm;roux limb:100cm.

Primary Outcomes

body mass idex
time frame: 24 months

Secondary Outcomes

time frame: 24 months
time frame: 24 months
blood pressure
time frame: 24 months
blood fat
time frame: 24 months

Eligibility Criteria

Male or female participants from 20 years up to 65 years old.

Inclusion Criteria: - Aged 20-65 years old - History of diabetes is less than 15 years - Fasting c-peptide≥1.6 - BMI≥21kg/m2; - Ability to understand the nature of the procedure and willing to follow postoperative routine lifestyle and checkups Exclusion Criteria: - Psychological and mental disorders - Serious important organs such as heart and lung disease cannot be tolerated surgery - Complex history of abdominal surgery in the abdominal cavity adhesion - Pregnancy or lactation

Additional Information

Official title The Curative Effect of the Length of the Jejunum Exclusion in Grstric Bypass Surgery for Type 2 Diabetes:a Randomized Controlled Trials
Principal investigator Tong Weidong, Professor
Description Currently, there is a growing evidence supports the efficacy of Roux-en-Y gastric bypass for the treatment of Type 2 diabetes mellitus. However,there still have a great controversy about the operation parameters. With randomized controlled trial, Patients of BMI>21kg/m2 with type 2 diabetes were randomly divided into two groups: short biliarypancreatic limb:50cm;long biliarypancreatic limb :100cm. The investigators followed-up 3,6,12,24 months of the change of BMI,FBG,HbA1c,Blood pressure,Blood fat after surgery.
Trial information was received from ClinicalTrials.gov and was last updated in February 2016.
Information provided to ClinicalTrials.gov by Third Military Medical University.