This trial is active, not recruiting.

Condition diabetes mellitus, type 2
Treatment viscous fiber
Sponsor St. Michael's Hospital, Toronto
Start date September 2015
End date September 2017
Trial size 1000 participants
Trial identifier NCT02629263, Viscous Fiber and GC


Purpose of Study (The Effect of Viscous Fiber on Glycemic Control (VF & GC)

According to the World Health Organization, about 347 million of the people are living with diabetes. (http://www.who.int/features/factfiles/diabetes/facts/en/, accessed on Nov. 23, 2015). Over the last decades, dietary fibers, namely dietary viscous fibers, have emerged as a nutrition component that may improve the postprandial glycemic response and hence aid in long term diabetes management. It is believed that supplementation with viscous fibers can control blood glucose by increasing viscosity of the gastric digesta, hence delaying gastric emptying and retarding entry of glucose into the bloodstream to result in a diminished postprandial rise in blood glucose. (Chutkan et al., 2012).

Currently, the evidence of the relationship between viscous fibers and diabetes is mixed. The purpose of this study is to conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) investigating the fasting glycemic and insulinemic effect of viscous fibers.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Time perspective retrospective

Primary Outcomes

HbA1c (%)
time frame: 3 weeks

Secondary Outcomes

Fasting Blood Glucose (mmol/l)
time frame: 3 weeks
Fasting Blood Insulin (pmol/l)
time frame: 3 weeks
Fructosamine (mmol/l)
time frame: 3 weeks
HOMA-IR (mU/mmol/l)
time frame: 3 weeks

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - Randomized Controlled Trials - Parallel or Crossover Design - Duration: >3 weeks - Food/ Supplements. - Soluble Fibers include: B-Glucan, Guar Gum, Konjac, Pectin, Psyllium. - Diabetes Biomarkers include: Fasting Blood Glucose, Fasting Insulin, Fructosamine, and HbA1c. Exclusion Criteria:

Additional Information

Official title The Effect of Viscous Fibre on Glycemic Control in Patients With Diabetes
Trial information was received from ClinicalTrials.gov and was last updated in August 2016.
Information provided to ClinicalTrials.gov by St. Michael's Hospital, Toronto.