This trial is active, not recruiting.

Condition mild cognitive impairment
Treatments verum tdcs, sham tdcs
Sponsor Wuerzburg University Hospital
Start date May 2015
End date April 2016
Trial size 50 participants
Trial identifier NCT02587338, Wuerzburg22/15


This study investigates the beneficial effects of prefrontal brain stimulation (with transcranial direct current stimulation [tDCS]) during working memory training in seniors with subjective memory impairments.The placebo-controlled double blinded study includes 50 elderly probants which were randomized into verum or sham tDCS.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking double blind (subject, investigator, outcomes assessor)
Primary purpose treatment
Left frontal anodal stimulation, supraorbital right cathodal stimulation
verum tdcs
Neuropsychological (Working memory) training for 30 minutes, 6 sessions tDCS during training with 2000 microampere left anadal, right cathodal
sham stimulation, same electrode positions
sham tdcs
Neuropsychological (Working memory) training for 30 minutes, 6 sessions tDCS during training with 0 microampere

Primary Outcomes

Neuropsychological performance in neuropsychological tests
time frame: 4 weeks

Secondary Outcomes

Brain activation measured with NIRS
time frame: 4 weeks

Eligibility Criteria

Male or female participants from 60 years up to 70 years old.

Inclusion Criteria: - native german speaker - between 60-70 years old - subjective memory impairment Exclusion Criteria: - psychiatric, neurological diseases - uncorrected hearing or vision deficits - actual psychopharmaca intake - metal parts in the head - medical electronical implants

Additional Information

Official title Verbesserung Kognitiver Fähigkeiten im Alter
Principal investigator Martin J. Herrmann, PD Dr
Trial information was received from ClinicalTrials.gov and was last updated in April 2016.
Information provided to ClinicalTrials.gov by Wuerzburg University Hospital.