Overview

This trial is active, not recruiting.

Condition autoimmune encephlitis in china
Sponsor Beijing Tongren Hospital
Start date May 2015
End date May 2017
Trial size 400 participants
Trial identifier NCT02561260, 2014-1-1101-2

Summary

In recent years, more and more previously thought to be unknown encephalitis was found to be a specific antigen associated encephalitis,but because of the lack of recognition in the clinic, usually been misdiagnosed as other causes of encephalitis. Therefore, it is urgent to establish a database of autoimmune encephalitis in Chinese population. The prospective clinical trial of atutoimmune encephalitis in China, by screening the autoimmune encephalitis associated antibody and summarizing the cases analysis, in order to provide evidence for clinical diagnosis and treatment of autoimmune encephalitis.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model case control
Time perspective prospective
Arm

Primary Outcomes

Measure
death
time frame: 30days

Eligibility Criteria

Male or female participants at least 6 months old.

Inclusion Criteria: 1. Older than 6 months. 2. Encephalopathy symptoms (change of mental state and consciousness level) persist for more than 24 hours; 3. At least one or more clinical features of the followings: fever, epilepsy, focal neurological deficiency symptoms, changes in CSF(cerebrospinal fluid inflammatory), changes in EEG (electroencephalogram), radiographic abnormalities; 4. Clinical suspected encephalitis, but conventional detected methods cannot make etiology clear. 5. Signed the informed consent. Exclusion Criteria: 1. Infants less than 6 months; 2. The metabolic encephalopathy; 3. Infectious encephalitis with clear pathogen clinically, referring the specific pathogenic microorganisms, including: bacteria, virus, fungus, parasite, spirochete and so on; 4. Non-infectious encephalitis with clear diagnosis clinically, including: multiple sclerosis, neuromyelitis optic, acute disseminated encephalomyelitis and so on.

Trial information was received from ClinicalTrials.gov and was last updated in September 2015.
Information provided to ClinicalTrials.gov by Beijing Tongren Hospital.