Overview

This trial is active, not recruiting.

Condition helicobacter infections
Treatment ppi(proton pump inhibitor)
Sponsor Asan Medical Center
Start date March 2014
End date February 2016
Trial size 30 participants
Trial identifier NCT02449941, 2014-0341

Summary

The purpose of this study is to know the distribution of HP in stomach before use of PPI, during use of PPI, and after stop of PPI.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model case-only
Time perspective prospective
Arm
Participants who are diagnosed with Helicobacter Pylori infection through ESD(endoscopic submucosal dissection) will be treated with PPI(proton pump inhibitor).
ppi(proton pump inhibitor)
Pre ESD (endoscopic submucosal dissection) Assessment atrophy and metaplasia in stomach, Check Helicobacter pylori Use of Proton Pump Inhibitor(PPI) for 2 months Post ESD 1 (After 2 months) Assess the distribution of helicobacter pylori after using PPI. Stop of Proton Pump Inhibitor(PPI) Post ESD 2 (After 4 months) Assess the distribution of helicobacter pylori after stop of PPI.

Primary Outcomes

Measure
Analysis the change of Helicobacter pylori distribution according to the use of proton pump inhibitor
time frame: Change in the distribution of Helicobacter Pylori(HP) at 4 months.

Secondary Outcomes

Measure
Analysis the change of HP distribution according to the use of PPI in atrophic change of stomach
time frame: Change in the distribution of Helicobacter Pylori(HP) at 4 months.

Eligibility Criteria

Male or female participants from 19 years up to 65 years old.

Inclusion Criteria: 1. Patients who are indicated to endoscopic resection due to gastric neoplasm 2. Aged between 19 to 65 years 3. Informed consent Exclusion Criteria: 1. Previous history of HP eradication 2. Previous history of PPI use within 6 months 3. No HP infection

Additional Information

Official title Distribution of Helicobacter Pylori According to the Use of Proton Pump Inhibitor
Principal investigator Ji Yong Ahn, Professor
Trial information was received from ClinicalTrials.gov and was last updated in May 2015.
Information provided to ClinicalTrials.gov by Asan Medical Center.