Overview

This trial is active, not recruiting.

Conditions overweight, obesity, physical activity
Treatments aerobic exercise, resistance exercise, sedentary option
Sponsor USDA Grand Forks Human Nutrition Research Center
Start date April 2015
End date November 2015
Trial size 80 participants
Trial identifier NCT02416882, GFHNRC405

Summary

This study tests whether different physical activity patterns are linked an individual's genes.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model crossover assignment
Masking open label
Arm
(Other)
Relative Reinforcing Value of aerobic exercise versus sedentary activity will be determined.
aerobic exercise
Subjects will sample and rate their liking of three cardiovascular machines (treadmill, cycle ergometer, elliptical step ergometer) to determine which one will be used during the test.
sedentary option
Subjects will rate their liking of three sedentary activities (reading magazines, playing puzzles, completing word games) as an alternative to exercise.
(Other)
Relative Reinforcing Value of resistance exercise versus sedentary activity will be determined.
resistance exercise
Subjects will sample and rate their liking of three different resistance training circuits (upper body, lower body, core) to determine which one will be used during the test.
sedentary option
Subjects will rate their liking of three sedentary activities (reading magazines, playing puzzles, completing word games) as an alternative to exercise.

Primary Outcomes

Measure
Relative Reinforcing Value (RRV) of Exercise as assessed by indicator (Subjects will sample and rate their liking of exercise)
time frame: 2 weeks

Eligibility Criteria

Male or female participants from 18 years up to 50 years old.

Inclusion Criteria: - BMI within 18.5-35.0 kg/m2 - Healthy enough to exercise - Active or inactive (not exercising at this time) Exclusion Criteria: - Taking any drugs that affect energy expenditure (e.g., thyroid, glucose-lowering drugs) - Have gained or lost more than 5% of body weight over the past 6 months - Use tobacco - Pregnant or lactating or plan to become pregnant in the next 6 months - Have any health conditions that prevent the individual from safely exercising (e.g., cardiovascular, liver, endocrine, or pulmonary diseases)

Additional Information

Official title Exercise Genes: Genomic Association With Exercise Reinforcement
Principal investigator James N Roemmich, PhD
Description The investigators propose that an individual's genetics are one factor that may be associated with the motivating aspect or attractiveness of exercise and therefore the choice to exercise rather than be sedentary. They propose to study the association of the genomic signatures with the reinforcing (motivating) value of different types of exercise. This has never been investigated and may uncover underlying mechanisms that would help to understand individual differences in exercise motivation. The ultimate impact of this work is a greater number of Americans being physically active, meeting the United States Department of Agriculture (USDA) dietary guidelines for physical activity, and maintaining a healthy body weight. This study will be funded and undertaken at the Grand Forks Human Nutrition Research Center (GFHNRC). The purpose will be to assess genetic underpinnings of the motivating value of resistance and aerobic exercise, and to determine whether the motivating value of aerobic and resistance exercise are associated with usual participation in these modes of exercise.
Trial information was received from ClinicalTrials.gov and was last updated in September 2016.
Information provided to ClinicalTrials.gov by USDA Grand Forks Human Nutrition Research Center.