This trial is active, not recruiting.

Condition pregnancy
Treatments clean cookstove, traditional cookstove
Sponsor University of Chicago
Start date September 2012
End date August 2017
Trial size 300 participants
Trial identifier NCT02394574, 12-1460


Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing countries.52-54 Of all environmental risks, such as unsafe water, poor sanitation, climate change and lead exposure, HAP accounts for the most mortality and DALY.55 Despite the magnitude of the problems associated with HAP, research on its health effects has been hindered by lack of accurate data on exposure and health outcomes. There are few studies available that report HAP exposures and development of adverse pregnancy outcomes from households using biomass fuels.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking open label
Primary purpose prevention
(Active Comparator)
Subjects will use ethanol stoves using bioethanol
clean cookstove
Subjects will use traditional firewood or kerosine cookstove and receive education on how to reduce air pollution exposures
traditional cookstove
Firewood / Kerosene

Primary Outcomes

Adverse Pregnancy Outcomes
time frame: At birth

Secondary Outcomes

Reduction in personal exposure to PM2.5, CO and PAH
time frame: At birth

Eligibility Criteria

Female participants up to 35 years old.

Inclusion Criteria: - Pregnant women who present to the hospital - Who cook exclusively with either kerosene or firewood - Before the fourteenth week of pregnancy as determined by ultrasound imaging Exclusion Criteria: - Smoking women or women with smoking family members - Women with a high-risk pregnancy defined as: - Women with uncontrolled hypertension - Women greater than 35 years old carrying their first child - Women having triplets or more - Women who have had a previous C-section - Women carrying babies with fetal abnormalities or as determined by the obstetrician.

Additional Information

Official title Household Air Pollution and Pregnancy Outcome
Principal investigator Christopher Olopade, MD
Trial information was received from ClinicalTrials.gov and was last updated in September 2016.
Information provided to ClinicalTrials.gov by University of Chicago.