This trial is active, not recruiting.

Condition heart failure
Treatment heart failure management
Sponsor University College, London
Collaborator National Institute for Cardiovascular Outcomes Research
Start date April 2012
End date March 2015
Trial size 63320 participants
Trial identifier NCT02353481, NICOR-Heart Failure


The aim of the study is to develop and assess a prognostic model for patient's survival up to 1 year after unscheduled acute heart failure hospital admission in England and Wales.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model cohort
Time perspective retrospective
All patients in the audit that meets the eligibility criteria
heart failure management

Primary Outcomes

All-cause mortality
time frame: 1 year

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - aged 18 and above - survived to discharge - have mortality status at 1 year post-discharge Exclusion Criteria: Non-index heart failure admissions during the study period will be excluded from the study sample.

Additional Information

Description There is a need for a prognostic model for 1 year survival of patients discharged alive after an unscheduled hospital admission for heart failure. This study aims to develop and validate a prognostic model that will enable management planning and facilitate the identification of therapeutic needs or targets. Also, it will assist care providers to predict or quantify patients' survival based on their baseline characteristics. The National Heart Failure Audit (NHFA) held by National Institute for Cardiovascular Outcomes Research (NICOR) is one of the largest available national heart failure registry. It includes data from unscheduled heart failure admissions in England and Wales. In the audit, heart failure diagnosis is defined as a diagnosis that has been confirmed by imaging or brain natriuretic peptide (BNP) measurement. This study will use NHFA data to develop and validate the proposed model.
Trial information was received from ClinicalTrials.gov and was last updated in February 2015.
Information provided to ClinicalTrials.gov by University College, London.