This trial is active, not recruiting.

Condition lupus nephritis
Treatment renal biopsy
Sponsor Hospital de Clinicas José de San Martín
Start date January 2014
End date November 2016
Trial size 36 participants
Trial identifier NCT02313974, HSM LuNe


At this moment, the duration of the treatment in Proliferative Lupus Nephritis has not been determined.

Almost 30 percent of patients in total remission during or after a treatment, will relapse in the first 5 years.

The factors associated to Renal relapses are not completly known. The investigators think that an histological control study performed to patient with complete remission for a year at the end of a 3 years treatment could help us to know which patients are going to relapse.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model cohort
Time perspective prospective

Primary Outcomes

Renal Flares
time frame: 2 years

Eligibility Criteria

Male or female participants from 18 years up to 70 years old.

Inclusion Criteria : - Patients between 18 and 70 years old with Proliferative Lupus Nephritis - 3 years treatment with a 6 month induction therapy and 2 years and a half of treatment maintenence Exclusion Criteria : - Membranous Nephropaty - Mesangial Nephropathy - Less than 3 years treatment - Less than 1 year of complete remission

Additional Information

Official title Lupus Flares and Histological Renal Activity at the End of the Treatment
Principal investigator Marcelo A De Rosa, Physician
Trial information was received from ClinicalTrials.gov and was last updated in September 2016.
Information provided to ClinicalTrials.gov by Hospital de Clinicas José de San Martín.