Overview

This trial is active, not recruiting.

Condition healthy subjects
Sponsor Isabelle Herter-Aeberli
Collaborator Federal Food Safety and Veterinary Office (Switzerland)
Start date March 2015
End date September 2016
Trial size 1430 participants
Trial identifier NCT02312466, SIS 2015

Summary

The aim of this study is to monitor iodine nutrition in Switzerland in order to inform the authorities regarding iodine content in iodized salt. As a proxy for the entire population the investigators will study school aged children, pregnant women and women of reproduction age.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Time perspective cross-sectional
Arm

Primary Outcomes

Measure
Median urinary iodine concentration in school aged children, pregnant women and women of reproductive age
time frame: Baseline

Secondary Outcomes

Measure
Population mean thyroglobulin
time frame: Baseline
Population mean thyroid stimulating hormone
time frame: Baseline
Population mean thyroxine
time frame: Baseline
Median urinary sodium concentration
time frame: Baseline
Median urinary creatinin concentration
time frame: Baseline

Eligibility Criteria

Male or female participants from 6 years up to 44 years old.

Inclusion Criteria: - Healthy - Living in Switzerland for at least 1 year - For pregnant women: singleton pregnancy Exclusion Criteria: - Major known medical illness: thyroid dysfunction, gastrointestinal or metabolic disorders and taking chronic medications - For women of reproductive age: pregnancy, breastfeeding - Use of X-ray or CT contrast agent or iodine containing medication within the past year

Additional Information

Official title Swiss National Iodine Survey 2015; A Cross-sectional Study to Assess Iodine Status in School Children, Women of Reproductive Age and Pregnant Women
Description In a national sample of school aged children (n=990), pregnant women (n=700) and women of reproductive age (n=700) urinary iodine will be determined in order to assess iodine nutrition in Switzerland. In addition, in both groups of women a blood sample will be taken for the determination of thyroid hormones, iron- and folate status. Questionnaires will be used for the determination of dietary iodine and salt intake as well as sociodemographic parameters.
Trial information was received from ClinicalTrials.gov and was last updated in October 2016.
Information provided to ClinicalTrials.gov by Swiss Federal Institute of Technology.