Overview

This trial is active, not recruiting.

Condition peribulbar anesthesia
Treatment dexmedetomidine
Phase phase 3
Sponsor King Saud University
Start date January 2014
End date January 2015
Trial size 90 participants
Trial identifier NCT02282787, E-14-1291

Summary

During LA in retinal surgery there is some problem as regard the lack of anaesthesia duration and unexpected globe movement .so many adjuvant was added to LA to overcome this disadvantages of LA such as clonidine and fentanyl .

The investigators hypothesis is adding dexmedetomidine to pribulbal blocking LA will prolong anaesthesia duration and improve globe akinesia and decrease intraoperative supplementation of LA.There are Many studies had described the effects of dexmedetomidine on peripheral nerve blocks, spinal but up to date no knowledge is available on the impact of dexmedetomidine adjuvant to local anaesthetic in ophthalmic surgery

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking double blind (subject, investigator)
Arm
(Experimental)
dexmedetomidine
Does adding 5 or 10 micron of DEXMEDETOMIDINE to peribulbar anesthesia is any different from regular peribulbar anesthesia practice?
(Experimental)
dexmedetomidine
Does adding 5 or 10 micron of DEXMEDETOMIDINE to peribulbar anesthesia is any different from regular peribulbar anesthesia practice?

Primary Outcomes

Measure
onset, duration of the motor and sensory block
time frame: 10 minutes from injection

Secondary Outcomes

Measure
observe the adverse effects of Dexmedetomidine
time frame: during and after surgery

Eligibility Criteria

Male or female participants from 40 years up to 90 years old.

Inclusion Criteria: - Adult patients - Going for elective vitreoretinal surgery. Exclusion Criteria: - History of coagulation abnormalities. - Allergy to local anesthetics. - Cardiac, hepatic or renal failure, - Chronic clonidine or analgesic therapy. - One-eyed patients

Additional Information

Official title DEXMEDETOMIDINE ADJUVANT TO LOCAL ANAESTHESIA FOR PERIBULBAR BLOCKS IN RETINAL SURGERY
Principal investigator Marwan Abouammoh, MD
Trial information was received from ClinicalTrials.gov and was last updated in March 2015.
Information provided to ClinicalTrials.gov by King Saud University.