Magnetic Resonance Elastography of Cardiac Transplant Rejection
This trial is active, not recruiting.
|Condition||acute graft rejection|
|Treatment||magnetic resonance elastography driver|
|Sponsor||Ohio State University|
|Start date||June 2014|
|End date||December 2017|
|Trial size||10 participants|
|Trial identifier||NCT02266914, 2013H0318|
Magnetic Resonance Elastography (MRE) for cardiac transplant patients.
|Intervention model||single group assignment|
Assess cardiac stiffness with Magnetic Resonance Elastography to determine cardiac transplant rejection
time frame: Up to 2 years
Male or female participants at least 18 years old.
Inclusion Criteria: - Patients must have undergone cardiac transplantation at the Ohio State University Ross Heart Hospital. - Patients must be able to lie flat on their back in the scanner for up to 60 minutes - Patient must be able to hold their breath for up to 15 seconds at a time. Exclusion Criteria: - Patients who are claustrophobic - Patients who are pregnant, due to potential risks to the fetus. - Patients with any unapproved, non-MRI safe metal/devices in their bodies.
|Official title||Magnetic Resonance Elastography of Cardiac Transplant Rejection|
|Principal investigator||Richard White, MD|
|Description||Patient will undergo MRE beginning 4-8 weeks post transplant, then with each scheduled cardiac biopsy through 7-8 months post transplant. Results of the MRE will be compared against results of the cardiac biopsy to determine if the non-invasive MRE can predict cardiac transplant rejection.|
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