Overview

This trial has been completed.

Condition ergogenic athletic performance
Treatment cycling exercise
Sponsor University of British Columbia
Collaborator Natural Sciences and Engineering Research Council, Canada
Start date January 2015
End date November 2015
Trial size 20 participants
Trial identifier NCT02255630, H14-02788

Summary

Athletes using inhaled β2-adrenoreceptor agonists (IBAs) win a disproportionate number of medals. However, most previous research has shown that β2 agonists do not improve exercise performance in either asthmatic or non-asthmatic athletes. Although the majority of these studies do not show an ergogenic effect, the small number of studies with extended exercise bouts (~60 minutes) do show an advantage. The investigators believe that a controlled yet sport-specific exercise protocol will elucidate this ergogenic effect. Because IBAs may have different effects on these two groups of athletes, the investigators will measure exercise performance in both female and male elite cyclists. The investigators hypothesize that athletes will perform better during a combination steady-state/sprint exercise task following salbutamol administration.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model single group assignment
Masking double blind (subject, investigator)
Primary purpose basic science
Arm
(Experimental)
Study participants will be exposed to 1600ug salbutamol 30min prior to exercise
cycling exercise
(Experimental)
Study participants will be exposed to 1600ug salbutamol 30min prior to exercise
cycling exercise

Primary Outcomes

Measure
Peak Power Output
time frame: peak power output of the final 30 seconds of the cycling bout will be assessed.

Eligibility Criteria

Male or female participants from 19 years up to 40 years old.

Inclusion Criteria: - maximal oxygen consumption of ≥60 and ≥55 mL⋅kg-1⋅min-1 or ≥5⋅L⋅min-1 and ≥4⋅L⋅min-1 for men and women Exclusion Criteria: - pregnant women - any history of uncontrolled respiratory or cardiac disease - smokers - diabetics

Additional Information

Official title The Effects of High-dose Salbutamol on Anaerobic Cycling Power
Principal investigator Michael S Koehle, MD, PhD
Trial information was received from ClinicalTrials.gov and was last updated in November 2016.
Information provided to ClinicalTrials.gov by University of British Columbia.