This trial is active, not recruiting.

Condition sports related concussion
Treatment riboflavin 400mg daily
Sponsor University of Virginia
Collaborator James Madison University
Start date September 2014
End date August 2015
Trial size 75 participants
Trial identifier NCT02235337, 17406


The purpose of this study is to investigate the effectiveness of riboflavin to decrease the duration of time for a student-athlete to return to participation in sports after a sports related concussion.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Intervention model single group assignment
Masking open label
Primary purpose treatment
riboflavin 400mg daily Vitamin B2

Primary Outcomes

Time to return to full participation in sports after a sports related concussion
time frame: 21 days or less

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - All UVa and JMU student-athletes over the age of 18 years old who are diagnosed with a sports related concussion Exclusion Criteria: - Less than 18 years old - Greater than 24 hours have elapsed since the concussion occurred. - The student-athlete has already participated in the study during which he/she took Riboflavin - Non-sports related concussion not incurred while participating in the sport or training for the sport. As an example, a student-athlete who sustains a concussion as a result of a motor vehicle accident will be excluded from the study for that concussion

Additional Information

Official title The Impact of Riboflavin on the Severity and Duration of Sports Related Concussion
Trial information was received from ClinicalTrials.gov and was last updated in September 2014.
Information provided to ClinicalTrials.gov by University of Virginia.