Overview

This trial is active, not recruiting.

Conditions breathing, mind-body practices, yoga, meditation
Treatment focused breathing
Phase phase 1
Sponsor Vanderbilt University
Start date August 2014
End date December 2015
Trial size 48 participants
Trial identifier NCT02226744, 131700

Summary

Mind-body practices, such as yoga, ta'i chi, mindfulness and biofeedback, commonly use slow breathing techniques to induce physiological and mental relaxation. Medical research suggests that slow breathing techniques induce physiological relaxation. This 6 week study will compare the effects of different types of breathing. The hypothesis is that different breathing techniques produce different physiological and mental changes.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking single blind (subject)
Primary purpose treatment
Arm
(Active Comparator)
Focused deep breathing techniques used to produce specific physiological and psychological states
focused breathing
(Active Comparator)
Focused deep breathing techniques used to produce specific physiological and psychological states
focused breathing

Primary Outcomes

Measure
Magnitude of changes in heart rate response to upright position
time frame: 10 minutes at baseline, 2 weeks and 6 weeks

Secondary Outcomes

Measure
Magnitude of changes in heart rate variability measured as ratio of low frequency to high frequency ratio components (Hz)
time frame: Baseline, 2 weeks, and 6 weeks
Magnitude of changes in catecholamines in response to upright position
time frame: 10 minutes at baseline, 2 weeks, and 6 weeks

Eligibility Criteria

Male or female participants from 30 years up to 50 years old.

Inclusion Criteria: - Age 30 to 50 years - English speaking Exclusion Criteria: - Hypertension - Heart disease: history of coronary artery disease, myocardial infarction, significant valvular disease, or congestive heart failure - Diabetes - Renal Disease - Anxiety Disorder - Depression - Other psychiatric conditions including schizophrenia or bipolar disorder - Attention-deficit-disorder or Attention-deficit-hyperactivity disorder - Musculoskeletal condition limiting capacity to perform yoga such as chronic lower back pain, chronic neck pain - Asthma - Chronic Obstructive Lung Disease - Obstructive Sleep Apnea - Smoker - Currently taking blood pressure medications, oral diabetic medication or insulin - Current participation in a mind-body practice/program - Current cancer other than non-melanoma skin cancer - Regular swimmer - Plays wind or brass musical instruments

Additional Information

Official title Focused Breathing Study
Principal investigator Gurjeet S Birdee, MD MPH
Trial information was received from ClinicalTrials.gov and was last updated in August 2014.
Information provided to ClinicalTrials.gov by Vanderbilt University.