Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.
This trial is active, not recruiting.
|Conditions||in vitro fertilization, assisted reproductive techniques|
|Treatment||day 0 denudation and time lapse culture on ivf-oocytes.|
|Sponsor||Regionshospitalet Viborg, Skive|
|Start date||June 2014|
|End date||January 2016|
|Trial size||100 participants|
|Trial identifier||NCT02222831, Skive-2014-BBP|
The aims of this study are to evaluate:
1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF.
2. the association between PIF status in embryo culture medium and embryo quality assessed by standard subjective parameters and morphokinetic development.
|Endpoint classification||safety/efficacy study|
|Intervention model||parallel assignment|
|Primary purpose||basic science|
time frame: Day 0-5 after oocyte pick-up
time frame: Day 1 after oocyte pick-up
Female participants from 18 years up to 40 years old.
Inclusion Criteria: - Standard IVF treatment - Body mass Index (BMI) between 18 and 30 - couples in which the male partner has normal sperm concentration and motility according to the World Health Organization (WHO, 2010) Exclusion Criteria: - Patients with less than four oocytes
|Official title||Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.|
|Principal investigator||Betina B Povlsen, MSc|
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