Does DNA Sperm Fragmentation Affects Embryo Morphokinetic?
This trial is active, not recruiting.
|Conditions||blastocyst time, pronuclear appearance, pronuclear fading, embryo compaction, cleavage times|
|Start date||February 2016|
|End date||December 2017|
|Trial size||60 participants|
|Trial identifier||NCT02214537, MADDA12201301|
The embryokinetics may be a new prognostic factor for choosing the human embryos with the highest implantation potential. In order to identify the factors that may affect the rate of embryo cleavage, there are many studies about morphokinetics and culture medium, oxygen tension, oocyte quality or type of medication used for ovarian stimulation. However there are no published data with respect to the influence of sperm DNA fragmentation in the embryo kinetic.
|Intervention model||single group assignment|
|Primary purpose||basic science|
Patients with MACS Selection
Time of pronuclear appearance in hours.
time frame: The mean time of appearance of pronuclei is 3.3951 hours in our patients. We are going to evaluate pronuclear appearence time in hours in our study groups
Male or female participants from 36 years up to 38 years old.
- Patients 36 to 38 years
- Fresh sample semen
- Minimum 6 oocytes
- Semen sample with at least 5 million/ml and at least 30% of progressive motile sperm.
- Patients younger than 36 or older than 38 years old
- Frozen semen sample
- Less tan 6 oocytes.
- Semen samples with less than 5 million / ml or less than 30% of motile sperm.
|Official title||Embryo Development Measure Depending on the DNA Sperm Fragmentation|
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