Overview

This trial is active, not recruiting.

Conditions overweight, obesity, weight loss
Treatments eat majority of calories in the morning, eat the majority of calories in the evening
Sponsor University of Tennessee
Start date July 2014
End date December 2016
Trial size 30 participants
Trial identifier NCT02204735, UTK_9560 B

Summary

While eating the majority of energy earlier in the day appears to have a positive effect on weight and cardiometabolic outcomes, it is not clear how eating earlier in the day influences other behaviors that have a circadian rhythm (sleep), other energy balance behaviors important for weight loss (physical activity), and self-reported feelings of appetite control (hunger and fullness). Thus the purpose of this study is to examine the influence of timing of eating on sleep patterns, physical activity, and self-reported feelings of appetite control. It is hypothesized that those who eat the majority of their calories earlier in the day will have greater weight loss than those who eat the majority later in the day.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking open label
Primary purpose treatment
Arm
(Experimental)
Participants will be instructed to consume 50% of their energy intake in their first eating bout, 30% in their second eating bout, and 20% in their third eating bout. For example, a participant prescribed a 1200 kcal/d diet needs to consume 600 kcal in their first eating bout, 360 kcal in their second bout, and 240 kcal in their third bout. Participants will be provided with sample meal plans meeting this prescription.
eat majority of calories in the morning
(Experimental)
Participants will be instructed to consume 20% of their energy intake in their first eating bout, 30% in their second eating bout, and 50% in their third eating bout. For example, a participant prescribed a 1200 kcal/d diet needs to consume 240 kcal in their first eating bout, 360 kcal in their second bout, and 600 kcal in their third bout. Participants will be provided with sample meal plans meeting this prescription.
eat the majority of calories in the evening

Primary Outcomes

Measure
weight
time frame: 0 and 8 weeks

Secondary Outcomes

Measure
physical activity
time frame: 0 and 8 weeks
sleep
time frame: 0 and 8 weeks
diet
time frame: 0 and 8 weeks
feelings of hunger and fullness
time frame: 0 and 8 weeks

Eligibility Criteria

Male or female participants from 25 years up to 65 years old.

Inclusion Criteria: - body mass index (BMI) between 27 and 45 kg/m2 - normal self-reported daily (weekday and weekend) wake-up time between 5 am and 8 am - normal, self-reported weekend wake-up time within two hours of their normal, self-reported weekday wake-up time - regularly (at least five nights/week) get at least six total hours of self-reported sleep Exclusion Criteria: - report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q) - report being unable to walk for 2 blocks (1/4 mile) without stopping - are currently participating in a weight loss program and/or taking weight loss medication or lost > 5% of body weight during the past 6 months - are diagnosed with type 1 or 2 diabetes - have had bariatric surgery or are planning to have bariatric surgery within the next 4 months - intend to move outside of the metropolitan area within the time frame of the investigation - are pregnant, lactating, < 6 months post-partum, or plan to become pregnant during the investigation - are taking mediation to aid in sleep - are shift workers/alternative shift workers that work outside of 7 am and 7 pm - have a metal allergy (which would prevent the ability of participant to wear the SenseWear® armband from BodyMedia® used in the proposed study).

Additional Information

Official title Timing of Meals for Weight Loss
Principal investigator Hollie Raynor, Ph, RD
Description Thirty adults will be provided an 8-week standard lifestyle intervention, that includes a 1200-1500 kcal/day, < 30% energy from fat dietary prescription, and a physical activity goal of 200 minutes/week. Participants will be randomized to one of two conditions differing in timing of energy consumed during eating bouts. Both conditions will limit the number of eating bouts/day to three. Participants will be instructed to eat their first eating bout within one hour of awakening and to consume their second and third eating bouts within five or six hours of their previous bout. Participants will be discouraged from eating at least one hour prior to going to sleep. During the intervention, participants will be instructed to self-monitor the time they wake up, the time of the start of each eating bout, and time they go to bed, as well as foods and beverages, and portion sizes, consumed. One condition will consume more energy earlier in the day (MORNING), thus energy intake will be split amongst the three eating bouts with 50% in the first bout, 30% in the second bout, and 20% in the last bout. The second condition will consume more energy later in the day (EVENING), thus energy intake will be split amongst the three eating bouts with 20% in the first bout, 30% in the second bout, and 50% in the last bout.
Trial information was received from ClinicalTrials.gov and was last updated in January 2016.
Information provided to ClinicalTrials.gov by University of Tennessee.