Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis
This trial is active, not recruiting.
|Treatments||metronidazole-ciprofloxacin gatifloxacin-clindamycin paste, creosote|
|Start date||June 2013|
|End date||December 2014|
|Trial size||100 participants|
|Trial identifier||NCT02196740, Tri-antibiotic-2014|
The triple antibiotic paste is widely used in young permanent teeth and permanent teeth root canal therapy with excellent antiantimicrobial effect.We hypothesize that its application in the treatment of periapical periodontitis of deciduous teeth is superior to other drugs currently in use as creosote.
|Endpoint classification||safety/efficacy study|
|Intervention model||parallel assignment|
|Masking||single blind (subject)|
Evidence of lesion healing confirmed by cone beam computed tomography and X-rays
time frame: 1 year
Male or female participants from 3 years up to 8 years old.
Inclusion Criteria: - clinical diagnosis of periapical periodontitis - must be primary teeth - must be 3~8 years old - the permanent tooth germ is complete and didnot be involved Exclusion Criteria: - blood disease - residual root that is advised to extract - serious periodontitis - allergy to the triple antibiotic paste
|Official title||Randomized Controlled Research of the Application of Triple Antibiotic Paste in Primary Teeth With|
|Description||We design to collect a group of patients presenting primary teeth with periapical periodontitis in certain criterion. We will divide the patients into two groups randomly.One group will get treated with triple antibiotic paste while the other with creosote.We want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of triple antibiotic paste.|
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