Prevalence of Vitreomacular Adhesion in Patients 40 Years and Older
This trial is active, not recruiting.
|Sponsor||Nova Southeastern University|
|Start date||May 2014|
|End date||January 2016|
|Trial size||1584 participants|
|Trial identifier||NCT02160340, 11221319Exp|
The purpose of this study is to evaluate the prevalence of vitreomacular adhesion (VMA) in patients 40 years and older using Spectral Domain Optical Coherence Tomography.
|United States||No locations recruiting|
|Other Countries||No locations recruiting|
|Birmingham, AL||Schaeffer Eye Center||no longer recruiting|
|Birmingham, AL||Leo Semes||no longer recruiting|
|Scottsdale, AZ||Schwartz Laser Eye Center||no longer recruiting|
|Sepulveda, CA||VA Greater Los Angeles Healthcare System||no longer recruiting|
|Broomfield, CO||Front Range Eye Associates||no longer recruiting|
|Coral Gables, FL||Aran Eye Associates||no longer recruiting|
|Fort Lauderdale, FL||Nova Southeastern University||no longer recruiting|
|Miami, FL||Retina Macula Specialists of Miami||no longer recruiting|
|Miami, FL||Murray Ocular Oncology and Retina||no longer recruiting|
|Winter Haven, FL||Vitreous and Retina Consultants||no longer recruiting|
|Morrow, GA||Clayton Eye Center||no longer recruiting|
|Indianapolis, IN||Indiana University College of Optometry||no longer recruiting|
|Olathe, KS||Grin Eyecare||no longer recruiting|
|Albuquerque, NM||Jones Eyecare||no longer recruiting|
|Portland, OR||Pacific University College of Optometry||no longer recruiting|
|McKinney, TX||Larry Alexander||no longer recruiting|
|Tacoma, WA||Retina and Macula Specialists||no longer recruiting|
|University Place, WA||Suburban Opticians||no longer recruiting|
Male or female subjects aged over 40 years with vitreomacular adhesion
What is the overall prevalence of Vitreomacular adhesion in the population 40 years and older?
time frame: Two years
Is there is a significant correlation between VMA and various maculopathies including diabetic macular edema, retinal vascular occlusion, and age-related macular degeneration?
time frame: 2 years
Male or female participants at least 40 years old.
Inclusion Criteria: 40 years and older - Clear media Exclusion Criteria: Less than 40 years of age - Prior history of vitreoretinal surgery or pharmacotherapy with intravitreal injection - Dense media opacity
|Official title||Phase 1 Study of Optical Coherence Tomography Images to Identify the Prevalence of Vitreomacular Adhesion and Associated Maculopathies|
|Principal investigator||Julie A Rodman, OD, MS, FAAO|
|Description||As a function of age, liquefaction of the vitreous body results in separation of the vitreous cavity from the retina. This posterior vitreous separation may be incomplete, leading to areas of residual VMA. These adhesions can result in maculopathies such as vitreomacular traction syndrome, macular hole, epiretinal membrane, cystoid macular edema, diabetic macular edema, neovascularization in diabetic retinopathy and retinal vein occlusion, exudative age-related macular degeneration, and myopic traction maculopathy. VMA may lead to pathological sequelae due to the static and dynamic anteroposterior tractional forces to the surface of the macula. The resultant complication will depend on the size and strength of the traction, with smaller areas of adhesion leading to greater traction. Identifying the prevalence of vitreomacular adhesion and its associated complications will yield valuable, new epidemiologic data, leading to improved diagnosis and management of patients with this condition. The prevalence of vitreomacular adhesion in specific age groups has not been investigated.|
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