Overview

This trial is active, not recruiting.

Condition osteoarthritis
Treatment yoga for knee osteoarthritis
Sponsor McMaster University
Start date May 2014
End date July 2014
Trial size 46 participants
Trial identifier NCT02146105, Labarge, Yoga_KneeOA

Summary

Keeping individuals with knee osteoarthritis physically active is critically important. Exercise is effective at reducing pain while improving physical function. However some exercises can overload the knee, and as a result, worsen knee pain and health of the knee joint. Yoga offers a foundation of static postures that improve muscle strength and joint flexibility. Using sophisticated technology that allows us to calculate the loads inside the knee, the investigators have selected yoga exercises that do not overload the knee joint. The investigators have designed a yoga exercise class that is ideal for people with knee osteoarthritis. The purpose of the study is to investigate whether these yoga exercises increase muscle strength and reduce knee pain in women with knee osteoarthritis. In addition, the investigators aim to show that these yoga exercises will also improve knee loads during activities, mobility and heart health. The investigators will ask 50 women with knee osteoarthritis to participate in a 12 week yoga exercise intervention, that requires attendance to 3 classes each week. The investigators will test strength of the leg muscles, pain, knee joint loads, mobility and cardiovascular health before and after the 12 week yoga exercise intervention.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Endpoint classification safety/efficacy study
Intervention model single group assignment
Masking open label
Primary purpose treatment
Arm
(Experimental)
An tailored arthritis-specific yoga program for women with knee osteoarthritis with the aim of increasing leg strength and alleviating knee pain related to the disease.
yoga for knee osteoarthritis
Yoga program specifically for women with knee osteoarthritis.

Primary Outcomes

Measure
Change in Knee Extensor Torque
time frame: Week 1 and Week 13
Change in Knee Pain
time frame: Week 1 and Week 13

Secondary Outcomes

Measure
Change in Six Minute Walk Test (6MWT)
time frame: Week 1 and Week 13
Change in 30-second Chair Stand
time frame: Week 1 and Week 13
Change in Timed Up and Go (TUG)
time frame: Week 1 and Week 13
Change in Stair Ascent and Descent
time frame: Week 1 and Week 13
Change in Subjective Scales
time frame: Week 1 and Week 13
Change in Cardiovascular Fitness
time frame: Week 1 and Week 13
Change in Biomechanical Outcomes
time frame: Week 1 and Week 13

Eligibility Criteria

Female participants at least 50 years old.

Inclusion Criteria: - Female - 50 years of age or older - Knee pain on most days of the week - Less than 30 minutes of morning stiffness - Bony enlargement - Bony tenderness to palpation - Signs of inflammation - Able to safely climb 2 flights of stairs without aid - Visited a family physician within the last 12 months Exclusion Criteria: - Any other forms of arthritis - Osteoporosis - History of patellofemoral symptoms - Active non-arthritic knee disease - Knee surgery - Use of cane or walking aid - Unstable heart condition - Neurological conditions - Skin allergy to medical tape - Hip or ankle injuries in past 3 months - Any injuries that would prohibit participation in yoga - Ipsilateral hip or ankle conditions - Currently receiving cancer treatment - Currently pregnant

Additional Information

Official title A Yoga Exercise Intervention Designed for Women With Knee Osteoarthritis
Principal investigator Monica R Maly, PhD
Description This study is an uncontrolled intervention study with repeated measures. The intervention is a 12-week supervised exercise class featuring biomechanically sound exercises for people with knee osteoarthritis. Measures of strength of the knee muscles, pain, biomechanics during walking and yoga, mobility and cardiovascular health will be included. Strength will be measured on a dynamometer. Pain will be assessed with questionnaires. Walking and three yoga postures will be observed using motion capture system integrated with force measurements from the floor. Mobility will be assessed during walking, stair-climbing and chair standing tasks. Cardiovascular health will be measured during a submaximal bicycle task.
Trial information was received from ClinicalTrials.gov and was last updated in June 2014.
Information provided to ClinicalTrials.gov by McMaster University.