Cross-sectional Study of Use of Speckle Method in Early Diagnosis of Cardiovascular Dysfunction
This trial is active, not recruiting.
|Treatment||speckle tracking echocardiography|
|Sponsor||University of Roma La Sapienza|
|Start date||January 2010|
|End date||March 2013|
|Trial size||700 participants|
|Trial identifier||NCT02132585, Spk-001|
Speckle tracking (STE) is a novel echocardiographic technique which permits calculation of myocardial velocities and deformation parameters such as strain and strain rate (SR). It is demonstrated that these parameters provide important insights into systolic and diastolic function, ischaemia, myocardial mechanics and many other pathophysiological processes of the heart. In this preliminary study, we investigated the role of STE in detection of early ventricular dysfunction in patients with Sjogren Syndrome, focusing on cardiorespiratory fitness.
|Observational model||case control|
Sjogren Patients evaluated with Speckle tracking echocardiography
Controls Speckle tracking echocardiography
Longitudinal Myocardial Strain reduction in Sjogren Patients
time frame: Baseline, 24 weeks
Association between 6minute-walking-test and Longitudinal strain reduction
time frame: baseline, 24 weeks
Male or female participants from 40 years up to 75 years old.
Inclusion Criteria: - Diagnosis of Sjogren Syndrome Exclusion Criteria: - previous cardiovascular events - unstable angina - stroke - diagnosis of heart failure - incapacity to provide an informed consent
|Official title||Cross Sectional Study of Use of Speckle Tracking Echocardiography in the Early Diagnosis of Cardiovascular Dysfunction and Performance in Sjogren Patients|
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