This trial is active, not recruiting.

Conditions chronic obstructive pulmonary disease, hypoxia
Treatment oxygen
Sponsor LHL Helse
Start date April 2014
End date March 2016
Trial size 16 participants
Trial identifier NCT02108925, 2013/2396


The project will test the hypothesis that lung ventilation during exercise is unaffected by oxygen supplementation. In addition, the acute effect of oxygen supplementation on dyspnoea, heart rate and blood pressure will be studied.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Intervention model single group assignment
Primary purpose treatment
Masking participant, investigator
Study subjects receive, in randomized order, either supplementary 30% oxygen or air (21% Oxygen) from a gas tight bag
supplementary oxygen during exercise

Primary Outcomes

Pulmonary ventilation
time frame: 1 hour

Secondary Outcomes

time frame: 1 hour
Heart rate
time frame: 1 hour
Blood pressure
time frame: 1 hour

Eligibility Criteria

All participants from 20 years up to 95 years old.

Inclusion Criteria: - Chronic obstructive pulmonary disease Exclusion Criteria: - No exacerbation - No active heart disease

Additional Information

Official title Oxygen Supply and Ventilation During Physical Exercise in Patients With Chronic Obstructive Pulmonary Disease
Principal investigator Anne Edvardsen, PhD
Trial information was received from ClinicalTrials.gov and was last updated in March 2017.
Information provided to ClinicalTrials.gov by LHL Helse.