Overview

This trial is active, not recruiting.

Conditions frailty, sarcopenia
Sponsor National Taiwan University Hospital
Collaborator National Health Research Institutes, Taiwan
Start date January 2011
End date December 2018
Trial size 350 participants
Trial identifier NCT02073370, 201010021R, EC0991002-E

Summary

Sarcopenia related mobility dysfunction was a preventable presentation in transitional variation of frailty. However, the definition, associated risk factors, clinical course and outcome of sarcopenia in Taiwanese older adults are still under-clarified and need for further study.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model cohort
Time perspective prospective
Arm
The research subjects will be culled from outpatients aged over 65 at NTUH; 1000 Taiwanese subjects aged 20-40 equally divided in both genders will be recruited in order to establish the norm of Taiwanese's skeletal muscle index.

Primary Outcomes

Measure
Domestic operation tool of sarcopenia for older adults
time frame: Baseline

Secondary Outcomes

Measure
Change from baseline in body composition during aging
time frame: up to 2 years

Eligibility Criteria

Male or female participants at least 65 years old.

Inclusion Criteria: - functional decline in recent one year - cognitive impairment - depressive symptom - mobility impairment - fall in recent one year - eating or feeding problems - weight loss - co-morbid conditions≧5 - tracking by different physician ≧3 in recent half year - poly-pharmacy≧8 in recent 3 months - hospitalization ≧1 in recent one year - emergency visits≧2 in recent one year - aged ≧ 80. Exclusion Criteria: - non-ambulatory (bed-ridden) patients - long-term residents at nursing homes - patients with a life expectancy shorter than six months - impairment in vision, hearing, or communicative ability, making convenience of clinical evaluation during the study period impossible.

Additional Information

Official title Clinical Evaluation, Biomarkers and Metabolomics of Sarcopenia in Frail Older Adults at Ambulatory Clinics
Principal investigator Ching-Yu Chen, MD
Trial information was received from ClinicalTrials.gov and was last updated in February 2014.
Information provided to ClinicalTrials.gov by National Taiwan University Hospital.