RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Cesarean Pain Relief
This trial is active, not recruiting.
|Conditions||cesarean section, pain, postoperative|
|Treatments||iv acetaminophen, placebo|
|Start date||January 2014|
|End date||December 2016|
|Trial size||116 participants|
|Trial identifier||NCT02046382, 13068|
This study is being done to evaluate the scheduled use of intravenous (IV) acetaminophen among cesarean section patients. The study hopes to find out if patients who receive scheduled IV acetaminophen for 48 hours following delivery have lower self-reported pain scores and use less narcotic pain medication than patients who do not receive IV acetaminophen.
|Intervention model||parallel assignment|
|Primary purpose||supportive care|
|Masking||participant, care provider, investigator|
Post operative pain
time frame: 48 hours
Narcotic associated side effects
time frame: 48 hours
Length of stay
time frame: 2-7 days
Female participants at least 18 years old.
Inclusion Criteria: - Age greater than or equal to 18 years - Scheduled cesarean section delivery - Patient of TriHealth's Faculty Medical Center or Tri-State Maternal Fetal Medicine Associates - Singleton pregnancy - Term delivery (greater than or equal to 37 weeks) - Spinal/epidural anesthesia with epidural analgesia (duramorph) - Use of pfannenstiel incision Exclusion Criteria: - Weight less than 50 kg - Allergy to study drugs (acetaminophen, oxycodone, duramorph, NSAIDS) - Multiple gestation pregnancy - Cesarean section for pre-term delivery (less than 37 weeks) - Fetal anomalies - Inability to use epidural duramorph at time of procedure - General anesthesia used - Vertical skin incision - Opioid addiction - Liver dysfunction (hepatitis, HELLP (hemolysis, elevated liver enzymes, and low platelet count), preeclampsia)
|Official title||Randomized Control Trial of IV Acetaminophen for Post Cesarean Delivery Pain Relief|
|Principal investigator||Donna Lambers, MD|
|Description||See Brief Summary|
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