This trial is active, not recruiting.

Condition asthma
Sponsor University of Edinburgh
Start date December 2013
End date January 2014
Trial identifier NCT02039102, 75764


Studies examining the sex differences in the epidemiology and morbidity patterns of asthma show that the rates of disease severity, healthcare utilisation, and poor quality of life are considerably higher in women than in men, and this has been attributed to endogenous and exogenous sex hormonal factors. Studies examining the impact of use of hormonal contraceptives on the risk of asthma and asthma-related conditions are few, yet findings are conflicting.

In the present study, the investigators utilize data from the Scottish Health Survey, a national representative sample, to investigate the associations between current use of hormonal contraceptives and the prevalence of self-reported doctor-diagnosed current asthma and wheezing symptoms in Scottish women. The investigators hypothesize that while current use of any hormonal contraceptives and combined oral pills are associated with higher prevalence of asthma and asthma outcomes, current use of progesterone-only contraceptives is not associated with asthma. A secondary aim of the current study is to examine whether there is evidence of any biological interaction between use of hormonal contraceptives and BMI in relation to the risk of asthma and asthma outcomes.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Time perspective cross-sectional

Primary Outcomes

Self-reported doctor-diagnosed current asthma
time frame: During the past 12 months

Secondary Outcomes

Self-reported wheezing symptom
time frame: During the past 12 months
Self-reported current treatment for asthma/wheeze
time frame: During the past 12 months

Eligibility Criteria

Female participants from 16 years up to 45 years old.

Inclusion Criteria: - Non-pregnant - Woman - 16-45 years old Exclusion Criteria: - Pregnant - Man - Younger than 16 years or older than 45 years old

Additional Information

Official title Use of Hormonal Contraceptives in Relation to Asthma and Wheezing Disorders in Scottish Women: a Population-based Cross-sectional Survey
Trial information was received from ClinicalTrials.gov and was last updated in January 2014.
Information provided to ClinicalTrials.gov by University of Edinburgh.