This trial is active, not recruiting.

Condition coronary artery disease
Treatment cbt
Sponsor National Taiwan University Hospital
Start date December 2013
End date December 2014
Trial size 30 participants
Trial identifier NCT01998555, 201306066RINC


The purpose of this study is to evaluate medical cost-effectiveness, reduce the psychological risk factors( including hostility, anxiety, depression, and perceived stress) in coronary artery disease (CAD) patients and enhance the regulation of the autonomic nervous system (including respiration rate, heart rate, distal blood vessel pulse, and finger temperament) through web-based cognitive -behavioral group therapy.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification safety/efficacy study
Intervention model parallel assignment
Masking open label
Primary purpose prevention
CAD receive web-based CBT group therapy
CAD waiting list will receive web-based CBT group therapy later

Primary Outcomes

Significant decrease of the psychological risk factors in web-based group CBT intervention group after an eight-week group intervention
time frame: Time point(s) at post-group intervention, 3 months, and 6 months follow up

Secondary Outcomes

Significantly reduce health care costs
time frame: intervention

Eligibility Criteria

Male or female participants from 30 years up to 70 years old.

inclusion: 1. coronary artery disease 2. regular medication exclusion: 1.Psychiatric diseases

Additional Information

Official title Development and Evaluation of a Web-based Group Cognitive-behavioral Therapy Program for Coronary Artery Heart Disease Patients
Principal investigator Bee-Horng Lue
Description Cognitive-behavioral therapy (CBT) is effective in reducing the level of anger, hostility and depression present in coronary artery disease (CAD) patients.In Taiwan, Weng et al. also confirmed the eight-week group CBT program not only diminished the emotion disturbances including anger, hostility and depression of CAD, but also significantly prolonged the coagulation time, thus reducing the rate of thrombosis formation. Even though the therapeutic effect of the CBT program was valid, this program is still not accessible for some patients in need because they are not aware of it, or they are restricted by time and transportation. Internet-based therapeutic intervention can overcome the obstacles to access this program at any time and in any place. Presently, structured CBT intervention is provided through the Internet and used widely by patients with physical or psychological problems such as smoking, obesity, or headaches, but not by CAD patients. Therefore, the purpose of this research is to evaluate the effects to reduce the psychological risk factors of a web-based group CBT program in CAD patients. Follow-up assessments will be performed after 3 and 6-month durations. The investigators expect that, after an eight-week group intervention, there will be significant decrease of the psychological risk factors. Moreover, the therapeutic effects can be maintained during the three- and six-month follow-up.evaluate In addition, web-based cognitive -behavioral group therapy will significantly reduce indirect medical costs (travel time and money).
Trial information was received from ClinicalTrials.gov and was last updated in August 2014.
Information provided to ClinicalTrials.gov by National Taiwan University Hospital.