This trial is active, not recruiting.

Condition healthy
Phase phase 0
Sponsor Pennington Biomedical Research Center
Collaborator Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Start date December 2013
End date June 2016
Trial size 150 participants
Trial identifier NCT01989104, 1R21HD073807-01A1, PBRC13019


The purpose of this study is to measure and link cadence (number of steps taken in a minute) to intensity of physical activity (e.g., low-intensity, moderate-intensity, vigorous-intensity) in children and adolescents (6-20 years-old), and to identify the cadence values corresponding to children's and adolescent's behavior during simulated free-living activities.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Time perspective cross-sectional
6-12 years of age
13-17 years of age
18-20 years of age

Primary Outcomes

time frame: 1 point
Metabolic cost
time frame: 1 point

Eligibility Criteria

Male or female participants from 6 years up to 20 years old.

Inclusion Criteria: - 6 to 20 years of age at the time of study enrollment - Not limited in the ability to walk Exclusion Criteria: - Hospitalization for mental illness within the past 5 years. - Any condition/medication that may affect heart rate response to exercise testing. - Previous history of, or clinical symptoms or signs of, cardiovascular disease, stroke or transient ischemic attacks, chest pain, unusual dyspnea during physical activity/exercise, severe ankle edema, or intermittent claudication. - Previous history of musculoskeletal injuries or problems causing severe pain during physical activity or exercise which interferes with daily activities. - Participant has a pacemaker or other implanted medical device (including metal joint replacements). - Participant is pregnant. - Participant is unable to complete all testing (1 or two sessions, as preferred) within a maximal two week period.

Additional Information

Official title Cadence and Intensity in Children and Adolescents (CADENCE-KIDS)
Principal investigator Catrine Tudor-Locke, PhD
Description Procedure - 1 visit - (approximately 3 hours in total) Day of Testing: Participant must be FASTED - No food for 4 hours before visit. All of the study procedures involving the participant will be completed in a single testing session (one-day - approximately 3 hours) at the Pennington Biomedical Research Center. If preferred, two visits on separate days can be scheduled to complete the protocol. - Screening questions (approximately 3-5 minutes) o Participants (or their legal guardian) will be asked to answer several screening questions to determine their eligibility for participating in CADENCE-KIDS. - Height and weight measures data collection (approximately 10 minutes) - Height will be measured. - Body weight and body fat percentage will be measured using a specialized scale. - Waist circumference will then be measured using a measuring tape. - Instrument attachment, treadmill walking, free-living activities (approximately 140 minutes) - Participants will be fitted with 10 devices (Digi-Walker Pedometer, NL-1000 Pedometer, StepWatch Activity Monitor, SenseWear Armband, GT3X+ accelerometer, GENEActiv Accelerometer, Actical Accelerometer, ActivPal Accelerometer, Polar Heart Rate Monitor, K4b2 Portable Metabolic Unit) to measure/monitor physical activity throughout the testing session. - Participants will then complete several low intensity free-living activities while their physical activity and oxygen uptake are concurrently assessed. Specifically, participants will rest in a chair, watch a portion of a child-friendly movie while seated in a chair, and color in a coloring book while seated in a chair. Each activity will last for 5 minutes and a 2 minute rest will occur between each activity. - Participants will then complete a series of walking bouts on a treadmill while their physical activity and oxygen uptake are concurrently assessed. The walking bouts start at 0.5 miles per hour and end at 5 miles per hour (0.5 miles per hour increments). Treadmill testing stops when the participant finishes the bout where they naturally select to jog/run, or following the completion of the last bout at 5.0 miles per hour, whichever occurs first. A 2 minute rest will occur between each treadmill bout. - Participants will then complete three additional free-living activities where physical activity and oxygen uptake continue to be concurrently measured. Specifically, participants will step up and down on an aerobic step at 88 beats per minute, dribble a basketball, and perform jumping jacks at 126 beats per minute (63 jumping jacks per minute). Each activity will last for 5 minutes and a 2 minute rest will occur between each activity.
Trial information was received from ClinicalTrials.gov and was last updated in September 2015.
Information provided to ClinicalTrials.gov by Pennington Biomedical Research Center.