This trial is active, not recruiting.

Condition thrombosis
Sponsor University of Chicago
Start date October 2012
End date October 2014
Trial size 1600 participants
Trial identifier NCT01988766, IRB12-1889


The purpose of this study is to compare the difference in thrombosis as a result of internal jugular (IJ) catheters versus peripherally inserted central catheter (PICC) lines. It is hypothesized that there will be a decreased rate of thrombosis in patients as a result of IJ catheters verses PICC lines.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model cohort
Time perspective retrospective
incidence of thrombosis in subjects who had PICC line placement
no incidence of thrombosis in subjects who had PICC line placement

Primary Outcomes

Incidence of Thrombosis
time frame: 15 months

Secondary Outcomes

Demographic Risk Factor Association with Risk of Thrombosis from PICC or IJ access
time frame: 15 months

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - subjects who had a PICC line placed at the University of Chicago between September 1, 2010 and December 31, 2011 Exclusion Criteria: - subjects under the age of 18

Additional Information

Official title Risk of Central Venous Stenosis in Patients With Chronic Renal Failure After IJ Line Placement
Principal investigator Mary Hammes, MD
Description In a cohort of patients from Sept 1, 2010 until December 31, 2011 with chronic kidney disease (CKD) has shown that the incidence of IJ thrombosis after short term catheter access occurred in only 1/26 subjects or 4%. The current study is being done to compare this experience with the incidence of thrombosis from PICC lines. A secondary aim will be to determine if variables such as level of renal function, prior history of thrombosis or atherosclerosis contribute to the risk of thrombosis when PICC lines are placed. This data will provide the first comparison of the incidence of thrombotic complications from short term IJ catheter access versus PICC lines.
Trial information was received from ClinicalTrials.gov and was last updated in January 2014.
Information provided to ClinicalTrials.gov by University of Chicago.