Overview

This trial is active, not recruiting.

Condition healthy
Treatments protein, calcium, porridge-based breakfast.
Sponsor Northumbria University
Start date November 2013
End date February 2014
Trial size 20 participants
Trial identifier NCT01986036, 32AN4

Summary

High-protein meals have previously been shown to acutely reduce appetite and energy intake. More recently, meals higher in calcium have also been shown to increase feelings of fullness, circulating insulin and intestinal peptide concentrations and reduce appetite sensations.

This study aims to assess whether calcium and protein act synergistically to acutely influence appetite and energy intake.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model crossover assignment
Masking double blind (subject, investigator)
Primary purpose basic science
Arm
(Sham Comparator)
Control breakfast low in protein and calcium. Porridge-based breakfast.
porridge-based breakfast.
Oats and water.
(Active Comparator)
High-protein breakfast.
protein
Milk-Protein
porridge-based breakfast.
Oats and water.
(Active Comparator)
High-calcium breakfast.
calcium
Soluble calcium powder.
porridge-based breakfast.
Oats and water.
(Experimental)
High-protein and calcium breakfast.
protein
Milk-Protein
calcium
Soluble calcium powder.
porridge-based breakfast.
Oats and water.

Primary Outcomes

Measure
Energy Intake
time frame: 60 min post test-meal

Secondary Outcomes

Measure
Subjective appetite sensations
time frame: 1 hr
Insulin concentrations
time frame: 1 hr
GLP-1 (7-36) concentrations
time frame: 1 hr
GIP concentration
time frame: 1 hr

Eligibility Criteria

Male or female participants from 18 years up to 40 years old.

Inclusion Criteria: - Male or Female - BMI 18.5-29.9 kg/m2 - Age: 18-40 years Exclusion Criteria: - Smokers - Food allergies - Metabolic disorders (ie. type 2 diabetes)

Additional Information

Official title The Acute, Synergistic Effects of Protein and Calcium on Appetite and Energy Intake
Principal investigator Javier T Gonzalez, PhD
Trial information was received from ClinicalTrials.gov and was last updated in April 2014.
Information provided to ClinicalTrials.gov by Northumbria University.