Overview

This trial is active, not recruiting.

Condition prostate cancer
Treatment mri
Sponsor Abramson Cancer Center of the University of Pennsylvania
Start date July 2012
End date April 2014
Trial size 15 participants
Trial identifier NCT01985932, UPCC 07812

Summary

This study is being done to evaluate the use of MRI during radiation treatment planning to identify areas of tumor within the prostate to aid in future treatment planning and targeting of prostate cancer. This study will be conducted at the University of Pennsylvania Health System. The study is projected to run for 18 months. Subjects will be male 18 or older with a prostate cancer diagnosis and treatment plansat the Department of Radiation Oncology.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Intervention model single group assignment
Primary purpose diagnostic

Primary Outcomes

Measure
Number of Adverse Events
time frame: 2 years

Eligibility Criteria

Male participants at least 18 years old.

Inclusion Criteria: - Age 18 or older - Male - Biopsy proven prostate cancer without evidence of metastatic disease - Planned definitive external beam RT with daily ERB and implanted Visicoil fiducial markers. - Prior fMRI-ec documenting an IPL 25 mm2 in axial bidimensional diameter product, concordant with intraprostatic tumor location as documented on transrectal ultrasoundbiopsy - Subject capable of giving informed consent for standard external beam RT and for the study. - No current contraindication that would prevent MRI or gadolinium contrast. Exclusion Criteria: - Metastatic disease - Lack of fMRI-ec documeneting an IPL 25 mm2 in axial bidimensional product, concordant with intraprostatic tumor location as documented on transrectal untrasound biopsy - Neoadjuvant androgen deprivation therapy greater than 10 weeks, defined from date of LHRH analog injection to date of fMRI-sim - Contraindication that would prevent MRI or gadolinium contrast - GFR 30 mL/min/1.73m2 per Crockoft-Gault formula.

Additional Information

Official title A Prospective Study Evaluating Non-Endorectal Coil Functional MRI Identification of Intraprostatic Tumor During Radiation Treatment Planning
Principal investigator Curtiland Deville, MD
Trial information was received from ClinicalTrials.gov and was last updated in December 2015.
Information provided to ClinicalTrials.gov by Abramson Cancer Center of the University of Pennsylvania.