Study of the Preservation of the Left Colic Artery on Rectum Cancer Surgery
This trial is active, not recruiting.
|Treatment||preserving the left colic artery|
|Start date||December 2012|
|End date||December 2014|
|Trial size||100 participants|
|Trial identifier||NCT01979029, Left Colic Artery|
To evaluate the influence to the blood supply of the anastomosis and the harvest of the No. 253 lymph nodes in different surgical methods--- preserving the left colic artery (LCA) and resect the No. 253 lymph node specifically in the radical resection of rectal carcinoma or dividing at the root of the inferior mesenteric artery (IMA) in the radical resection of rectal carcinoma.
|Intervention model||parallel assignment|
|Masking||single blind (subject)|
The blood pressure of the arterial arcade
time frame: baseline
Male or female participants from 18 years up to 85 years old.
- Patients coming to FirstJilinU diagnosed rectum cancer by endoscopy and pathology.
- The rectum cancer is the first malignant neoplasm the patient has got.
- The cancer is solitary, and is 5cm to 20cm to the anus.
- The surgical method is limited to Dixon.
- Being in the acute phase of inflammation before operation and emergency surgery.
- Patients combined coronary heart disease，aortic stenosis，Arteritis。
- Discovering macrometastasis before or in the operation.
- The rectum cancer that can't be radical resected.
|Official title||Affection on Anastomotic Blood Flow and the Lymph Nodes Dissection Between Division at the Root of the Inferior Mesenteric Artery and Preserving the Left Colic Artery in Rectum Cancer Surgery|
|Description||Methods: The patients who got rectal carcinoma are divided into two groups. Both groups will receive the radical resection of rectal carcinoma. We preserve the left colic artery and resect the No. 253 lymph node specifically in Group A and divide at the root of the inferior mesenteric artery in Group B, We insert a trocar into the arterial arcade at the proximal site of the anastomosis and measure the blood pressure of the arterial arcade in the operation, which can reflect the blood supply of the anastomosis. Besides, We will measure the length of the colon from the anastomosis to the level of the root of the IMA. Expecting Results：The blood pressure of the arterial arcade in Group A will be higher than that in Group B. And the patients in Group A will have less chance to get anastomotic fistula. Expecting Conclusions: Preserving the LCA and resecting the No. 253 lymph node specifically in the radical resection of rectal carcinoma can improve the blood supply of the anastomosis and decrease the incidence of anastomotic fistula, and won't affect the harvest of the No. 253 lymph node.|
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