This trial is active, not recruiting.

Condition type 2 diabetes
Sponsor University of Aarhus
Start date January 2014
End date August 2015
Trial size 20 participants
Trial identifier NCT01961024, ES-0006


In thise study, we aim to determine the effect of meal fat on VLDL-TG kinetics in type 2 diabetic and healthy subjects matched for BMI in order to elucidate the potential pathophysiological differences in VLDL-TG FA channeling towards oxidation and storage in abdominal and leg subcutaneous adipose tissue. Specifically, we want to measure, by way of fat and muscle biopsies, the quantitative postprandial storage of VLDL-TG FA's in skeletal muscle and adipose tissue in relation to a series of tissue specific proteins and enzymes that might be involved in regulating skeletal muscle and adipose tissue FA storage.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model cohort
Time perspective cross-sectional

Primary Outcomes

VLDL-TG storage in adipose tissue
time frame: 3 hours

Secondary Outcomes

18F-THA fractional storage
time frame: 6 Hours

Eligibility Criteria

Male participants from 30 years up to 70 years old.

Inclusion Criteria: - Written consent Exclusion Criteria: - Known diseases - Alcohol abuse - Smoker - Regular use of medicine

Additional Information

Official title Postprandial VLDL-TG Metabolism
Trial information was received from ClinicalTrials.gov and was last updated in November 2015.
Information provided to ClinicalTrials.gov by University of Aarhus.