Postprandial VLDL-TG Metabolism
This trial is active, not recruiting.
|Condition||type 2 diabetes|
|Sponsor||University of Aarhus|
|Start date||January 2014|
|End date||August 2015|
|Trial size||20 participants|
|Trial identifier||NCT01961024, ES-0006|
In thise study, we aim to determine the effect of meal fat on VLDL-TG kinetics in type 2 diabetic and healthy subjects matched for BMI in order to elucidate the potential pathophysiological differences in VLDL-TG FA channeling towards oxidation and storage in abdominal and leg subcutaneous adipose tissue. Specifically, we want to measure, by way of fat and muscle biopsies, the quantitative postprandial storage of VLDL-TG FA's in skeletal muscle and adipose tissue in relation to a series of tissue specific proteins and enzymes that might be involved in regulating skeletal muscle and adipose tissue FA storage.
VLDL-TG storage in adipose tissue
time frame: 3 hours
18F-THA fractional storage
time frame: 6 Hours
Male participants from 30 years up to 70 years old.
Inclusion Criteria: - Written consent Exclusion Criteria: - Known diseases - Alcohol abuse - Smoker - Regular use of medicine
|Official title||Postprandial VLDL-TG Metabolism|
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