Gene Expression in Patients With Epiretinal Membranes
This trial is active, not recruiting.
|Condition||proliferative diabetic retinopathy|
|Sponsor||Medical University of Silesia|
|Collaborator||Department of Molecular Biology, Medical University of Silesia|
|Start date||June 2012|
|End date||September 2013|
|Trial identifier||NCT01946451, SilesianMU|
The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in proliferative diabetic retinopathy. Possible correlations between messenger ribonucleic acid (mRNA) levels of these genes were also identified.
|Observational model||case control|
Gene expression in patients with idiopathic and secondary epiretinal membranes in proliferative diabetic retinopathy.
time frame: The period between the diagnosis of the ERMs and the actual surgery for the condition was between 2 and 43 months.
Male or female participants at least 55 years old.
Inclusion Criteria: - Caucasian race, - both males and females, - aged ≥ 55 years, - suffering from idiopathic ERMs or secondary ERMs in proliferative diabetic retinopathy (PDR). - Presence of ERM was proven in optical coherence tomography (OCT) examination. Exclusion criteria: - aged < 55 years, - systemic connective tissue disease, - active inflammatory process
|Official title||Gene Expression and Their Correlations in Patients With Idiopathic and Secondary Epiretinal Membranes in Proliferative Diabetic Retinopathy|
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