Overview

This trial is active, not recruiting.

Condition chronic periodontitis
Treatments scaling root planing, propolis
Sponsor Rajarajeswari Dental College & Hospital
Start date December 2012
End date August 2013
Trial size 20 participants
Trial identifier NCT01943877, 971987

Summary

This study was conducted to evaluate by clinical and microbiological parameters the effect of locally delivered propolis as an adjunct to scaling and root planing in the treatment of chronic periodontitis.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking single blind (subject)
Primary purpose treatment
Arm
(Experimental)
scaling root planing
scaling root planing
propolis
experimental
(Sham Comparator)
scaling root planing
scaling root planing

Primary Outcomes

Measure
Change in the probing pocket depth and clinical attachment level
time frame: three time points of baseline,2 weeks, 4 weeks

Secondary Outcomes

Measure
change in gingival index and microbiological changes
time frame: three time points baseline, 2 weeks, 4 weeks.

Eligibility Criteria

Male or female participants from 25 years up to 50 years old.

Inclusion Criteria: - good general health - chronic periodontitis - minimum of 20 natural teeth with at least one pocket per quadrant - probing depth (PD) between 5 and 8 mm. Exclusion Criteria: - subgingival instrumentation within 3 months - antibiotic therapy within 3 months prior to the start of the study; - smokers - pregnant or nursing women - intolerance or allergy to honey products

Additional Information

Official title Propolis In The Treatment Of Chronic Periodontitis - A Clinicomicrobiologic Study
Description Materials and Methods: 20 subjects diagnosed with chronic periodontitis were recruited to participate in split-mouth design and provided informed consent. Subgingival plaque sampling and clinical recording at baseline, 15 days and 1 month was performed. The patients received scaling and root planing, followed by Propolis administration subgingivally in the test sites. Significant differences between test and control were evaluated using the Mann-Whitney U test and Wilcoxon rank test.
Trial information was received from ClinicalTrials.gov and was last updated in September 2013.
Information provided to ClinicalTrials.gov by Rajarajeswari Dental College & Hospital.