This trial is active, not recruiting.

Conditions burns, trauma
Treatment micro-imaging
Sponsor University of South Alabama
Start date April 2012
End date December 2016
Trial size 200 participants
Trial identifier NCT01922960, 12-092


Predict the development of multiple organ failure in patients with trauma and severe burns.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Intervention model single group assignment
Masking open label
Primary purpose basic science
Sublingual or subconjunctival micro-imaging of the microcirculation taken for 3 minute intervals at certain timepoints. Timepoints for burn/trauma subjects: Day0, Day1,Day2,Day6 & Day7 Timepoints for general surgery population: post-induction, prior to resection, after resection,& closing of surgical wound.

Primary Outcomes

dysfunctional capillary density correlates with development of multiple organ failure
time frame: approximately 1 year to assess outcome measure

Eligibility Criteria

Male or female participants from 19 years up to 80 years old.

Inclusion Criteria: - Patients with severe burns/trauma ages 19-80. Patients undergoing elective abdominal or cardiothoracic surgery ages 19-69 years old Exclusion Criteria: - Patients undergoing elective surgery < 19 years old.

Additional Information

Official title Microcirculatory Assessment in Patients With Trauma and Severe Burns
Description Microvascular alterations are frequently seen in patients with sepsis, trauma, burns and those who are hemodynamically uncompensated(Shock). The use of the Microscan is a non-invasive approach to visualize and assess impaired mucosal microcirculation in order to identify early on patients who are predisposed for MOF (multiple organ failure)
Trial information was received from ClinicalTrials.gov and was last updated in January 2016.
Information provided to ClinicalTrials.gov by University of South Alabama.