Metabolomics of Liver Regeneration Following Partial Hepatectomy in Healthy Living Liver Donors
This trial is active, not recruiting.
|Sponsor||Baylor Research Institute|
|Start date||August 2013|
|End date||August 2018|
|Trial size||20 participants|
|Trial identifier||NCT01922323, 013-140|
The PI will study metabolism during liver regeneration in living liver donors
Characterized Metabolic Changes during liver regeneration
time frame: one year after donation
Male or female participants from 18 years up to 60 years old.
- Potential donor must be in excellent medical and psychological health.
- Potential donor must be between the ages of 18 and 60.
- Must have a compatible blood type to the recipient.
- Must have health care coverage for non-donor related health issues that arise post donation
- Recipient and donor must have compatible body size.
- Donors Body Mass Index (BMI) must be less than 30.
- All previous donor abdominal surgeries will be reviewed on a case by case basis by the surgeon.
- Positive blood test for Human Immunodeficiency Virus, Hepatitis C virus, Hepatitis B virus
- The size of the donor liver is not large enough to safely resection and still retain enough volume to function normally after the surgery.
- Liver biopsy show liver cirrhosis or early stages of HCC.
|Official title||Metabolomics of Liver Regeneration Following Partial Hepatectomy in Healthy Living Liver Donors|
|Principal investigator||Giuliano Testa, MD|
|Description||Samples of blood and urine will be collected from study participants at defined timepoints. The samples will be evaluated to study the metabolism of the regenerating liver after a portion of the liver has been donated from a living donor.|
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