Overview

This trial is active, not recruiting.

Condition depression
Treatment rumination-focused cognitive behavior therapy
Sponsor University of Illinois at Chicago
Start date March 2013
End date July 2017
Trial size 33 participants
Trial identifier NCT01905267, 2012-0689

Summary

The Pediatric Mood Disorders Program at the University of Illinois at Chicago is conducting a research study examining how mindfulness can help teenagers stay healthy and prevent depression relapse.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking single blind (outcomes assessor)
Primary purpose prevention
Arm
(Experimental)
Participants randomized to the experimental condition will receive 8 weeks of individual treatment with Rumination-Focused Cognitive Behavior Therapy
rumination-focused cognitive behavior therapy
This intervention targets rumination and other maladaptive forms of emotion regulation such as suppression and avoidance and provides skills training in effective coping strategies. Mindfulness is a key component of this intervention as a strategy for disengaging from one's thoughts. Strategies from Dialectical Behavior Therapy (DBT), such as the use of effective interpersonal skills, are also included as methods for regulating strong emotion. Rumination-Focused Cognitive Behavior Therapy is a structured, manual based program designed to be delivered weekly over eight weeks. Sessions are 60-90 minutes in length.
(No Intervention)
Participants randomized to the control arm will complete questionnaires and receive mood monitoring for the duration of the study

Primary Outcomes

Measure
Change from Baseline in the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children Present and Lifetime Version Criteria for Current Major Depressive Episode
time frame: Baseline, 8 week, 6 month, 12 month, 18 month, 24 month

Secondary Outcomes

Measure
Change From Baseline in Children's Depression Rating Scale - Revised
time frame: Baseline, 8 week, 6 month, 12 month, 18 month, 24 month

Eligibility Criteria

Male or female participants from 12 years up to 18 years old.

Inclusion Criteria: - between the ages of 12 and 18 - history of major depressive disorder Exclusion Criteria: - braces - afraid of small spaces

Additional Information

Official title Mindfulness Intervention to Study the Neurobiology of Depression
Principal investigator Rachel H Jacobs, PhD
Description Study involves: - Brain scan using fMRI technology - Questions about mood and behavior - Meeting with a clinician - Possibility of 8 weekly treatment sessions using mindfulness - Ongoing assessment of depression for next 2 years Eligible participants will be compensated for their time.
Trial information was received from ClinicalTrials.gov and was last updated in March 2016.
Information provided to ClinicalTrials.gov by University of Illinois at Chicago.