This trial is active, not recruiting.

Condition diabetes mellitus type 2
Treatment non surgical periodontal treatment
Sponsor Pakistan Institute of Medical Sciences
Start date December 2012
End date September 2013
Trial size 184 participants
Trial identifier NCT01901926, Salman-0509


The purpose of this study is to determine the effects of non surgical periodontal treatment on glycemic control in type II diabetics.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking open label
Primary purpose treatment
(Active Comparator)
Periodontal Treatment in the form of Full mouth scaling and root planning will be given at one time only i.e. at baseline after full mouth dental checkup. Checkup will be repeated at 3, 6 & 9 month interval along with HbA1C levels
non surgical periodontal treatment
one time intervention in the form of scaling and root planing
(No Intervention)
this group will only receive detailed dental check ups at the specified time 0, 3, 6 and 9 months respectively and there will be no scaling done. HbA1C levels will be estimated at the above specified times

Primary Outcomes

Change in HbA1C levels from base line at 3, 6 and 9 months
time frame: 3 months, 6 months, 9 months

Secondary Outcomes

Bleeding on Probing
time frame: Base Line, 3 months, 6 months and 9 months
Clinical Attachment Loss
time frame: Base Line, 3 months, 6 months, 9 months
Periodontal Pocket Depth
time frame: Base Line, 3 months, 6 months, 9 months

Eligibility Criteria

Male or female participants from 20 years up to 70 years old.

Inclusion Criteria: - Diagnosed patients of Type 2 Diabetes Mellitus for at least 2 years - HbA1C values >6.5 % as per ADA criteria - non smokers - Patients with at least 16 standing teeth - At least 8 teeth with one site having Mild to Moderate periodontal disease Exclusion Criteria: - Smokers - Type 2 Diabetics with complications e.g. renal, ophthalmic etc - Patients with chronic infections - Patients who get hospitalized or have to change their medications during the course of study

Additional Information

Official title Impact of Non Surgical Periodontal Treatment on Glycemic Control in Type II Diabetics
Principal investigator Salman Aziz, FCPS, MFDS
Description The selected patients in treatment group will be given mechanical periodontal treatment in the form of scaling and root planning while the non intervention group patients will not receive treatment until the end of the trial.
Trial information was received from ClinicalTrials.gov and was last updated in July 2013.
Information provided to ClinicalTrials.gov by Pakistan Institute of Medical Sciences.