Physical Activity in Reducing Joint Pain in Breast Cancer Survivors Receiving Hormone Therapy
This trial is active, not recruiting.
|Conditions||joint pain, breast cancer|
|Treatment||walk with ease|
|Sponsor||University of North Carolina, Chapel Hill|
|Start date||August 2013|
|End date||October 2015|
|Trial size||78 participants|
|Trial identifier||NCT01900418, 13-2321|
For post-menopausal women diagnosed with hormone-receptor positive breast cancer tumors, aromatase inhibitors (AIs) are the standard adjuvant hormone treatment to prolong disease-free survival and time-to-recurrence. Unfortunately, joint pain/stiffness/achiness (arthralgia) is a common side-effect of AIs. This "proof-of-concept" study explores how an evidence-based physical activity (PA) program- the Arthritis Foundation's Walk with Ease (WWE) program- can be adapted for breast cancer survivors on AI therapy to: 1) Help them maintain or achieve recommended levels of PA, 2) reduce their joint pain/stiffness/achiness, and 3) thereby enable them to remain on AI therapy as prescribed.
|United States||No locations recruiting|
|Other Countries||No locations recruiting|
|Endpoint classification||safety/efficacy study|
|Intervention model||factorial assignment|
|Masking||single blind (subject)|
|Primary purpose||health services research|
Walk with Ease
Wait list control receiving the active intervention 6 weeks later.
Self-reported joint pain
time frame: 6 weeks
time frame: 6 weeks
Female participants from 21 years up to 99 years old.
Inclusion Criteria: - Taking an aromatase inhibitor as adjuvant treatment for State I, II, or II breast cancer for at least 4 weeks - Experiencing more than mild joint pain/symptoms - 21 or older - have permission from physician to engage in moderate intensity physical activity Exclusion Criteria: - Undergoing chemotherapy and/or radiation therapy at any time during the study period - Scheduled for major surgery during the study period - Presently engaged in high levels of physical activity on a daily basis - Less than 21 years of age - Unable to walk or engage in moderate intensity physical activity
|Official title||Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy|
|Principal investigator||Leigh F Callahan, PhD|
Call for more information